Affiliations

• Department of Veterinary Biomedicine, Faculty of Veterinary Medicine, Université de Montréal
• Associate researcher, CHUM Research Center

Research expertise

• Analytical and medicinal chemistry
• Proteomics
• Pharmacology
• Pharmaceutical Sciences

Main research projects

• Study of the neurochemical genesis of pain and nociception using model organisms (e.g. C. Elegans) and experimental models.
• Study of the proteolytic control mechanisms of endogenous neuropeptides.
• Development of new therapeutic strategies for the treatment of pain.
• Study of the pharmacokinetics and metabolism of analgesics as well as drug interactions to study the risks of polypharmacy.

Approaches used

• Liquid chromatography coupled to mass spectrometry.
• Caenorhabditis Elegans (C. Elegans) as a model organism to study nociception.
• Thermotaxis and chemotaxis.
• Quantitative proteomics; label-free quantification, isobaric labeling quantification, targeted proteomics (MRM or PRM).
• Bioinformatics, statistical and functional enrichment analysis.

 Keywords

Pain, Analgesia, Neuropharmacology, Neurochemistry, Proteomics