Affiliations
- Department of Veterinary Biomedicine, Faculty of Veterinary Medicine, Université de Montréal
- Associate researcher, CHUM Research Center
Research expertise
- Analytical and medicinal chemistry
- Proteomics
- Pharmacology
- Pharmaceutical Sciences
Main research projects
- Study of the neurochemical genesis of pain and nociception using model organisms (e.g. C. Elegans) and experimental models.
- Study of the proteolytic control mechanisms of endogenous neuropeptides.
- Development of new therapeutic strategies for the treatment of pain.
- Study of the pharmacokinetics and metabolism of analgesics as well as drug interactions to study the risks of polypharmacy.
Approaches used
- Liquid chromatography coupled to mass spectrometry.
- Caenorhabditis Elegans (C. Elegans) as a model organism to study nociception.
- Thermotaxis and chemotaxis.
- Quantitative proteomics; label-free quantification, isobaric labeling quantification, targeted proteomics (MRM or PRM).
- Bioinformatics, statistical and functional enrichment analysis.
Keywords
Pain, Analgesia, Neuropharmacology, Neurochemistry, Proteomics
Thematics
Teams
Keywords
This content has been updated on 26 January 2024 at 11 h 32 min.