Affiliations
- Department of Neuroscience - Faculty of Medicine
- Member of the GRSNC
Research expertise
- Organization and function of hippocampal synaptic circuits
- Plasticity of synaptic transmission in learning and memory
- Synaptic dysfunction in brain diseases (autism, intellectual disability, and epilepsy)
Main research projects
- Regulation of the hippocampal network and memory by synaptic plasticity of inhibitory interneurons
- Control of mRNA translation in learning, memory and autism disorders (collaboration N. Sonenberg)
- Heterogeneous regulation of hippocampal inhibitory synapses by astrocytes (collaboration R. Robitaille)
- Dysfunctions of inhibitory interneurons in genetic mouse models of epilepsy (collaboration E. Rossignol)
Approaches used
- Electrophysiology (patch-clamp, field potential) on slices in vitro
- 2-photon cell imaging (in vitro, in vivo)
- Molecular biology and transgenic mice
- Behavioral tests (learning and memory, virtual reality)
- Optogenetics and chemogenetics
Keywords
Learning and memory, Inhibitory interneurons, Autism, Epilepsy, Hippocampus
Thematics
Teams
Keywords
This content has been updated on 11 April 2024 at 15 h 12 min.